Barely Significant
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Real-world data of cadonilimab in recurrent or metastatic cervical cancer in China: a multicentric study.

Front Immunol · 2025 · PMC12301402 · PMID 40726978

2
hedged sentences
0.0840
closest p · 1.7× alpha
0.2350
boldest claim

The sentences

did not reach statistical significanceP = 0.084so close (0.05 < p ≤ 0.1)
Although this trend did not reach statistical significance ( P = 0.084), likely due to the limited sample size, the observed pattern suggests a potential predictive role of PIK3CA mutations for immunotherapy responsiveness in selected patients.

also in 33,519 other papers

a numerical trendP = 0.235not close (p > 0.1)
Subgroup analysis showed a numerical trend toward longer median PFS in patients with PD-L1 CPS ≥ 1 compared with CPS < 1 (14.0 vs. 12.8 months; P = 0.235).

also in 268 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.