Novel set of plasma proteins classifies Alzheimer's dementia in African American individuals with high accuracy.

71 , 72 Of note, several plasma protein predictors (HSPA1A, APOD, TAGLN, C7) were reported as highly significant differentially expressed genes in a review of cell‐specific transcriptional signatures of vascular cells in AD. 73 Together these findings may reflect AD‐related changes in the vasculature and highlight the potential to capture central AD pathophysiology in a peripheral tissue.

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Two plasma protein predictors CANT1 ( p = 0.01) and CD209 ( p = 0.004) were nominally significant, but did not survive FDR correction.

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