Telomere biology disorders in lung transplantation: Clinical challenges and management strategies.

7 , 25 , 39 , 45 , 46 Newton et al observed that short telomeres were more frequently associated with restrictive-CLAD, although this did not reach statistical significance. 35 Interestingly, one study found that short TL in the donor was associated with worse CLAD-free survival. 46 The increased CLAD risk in patients with TBD may be related to immune dysregulation, greater susceptibility to respiratory infections and the need to reduce immunosuppression due to cytopenias. 3.

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