Barely Significant
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Elderly stroke burden: a comprehensive global study over three decades.

Front Aging · 2025 · PMC12303880 · PMID 40734668

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an increasing trendno p-value reported
From 1990 to 2021, there was an increasing trend in DALYs cases in all age groups of the elderly population.

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a decreasing trendno p-value reported
From 1990 to 2021, the total number of stroke deaths in the global elderly population increased from 4,082,291.7 (95% UI, 3,764,144.994–4,325,839.34) to 6,194,922.11 (95% UI, 5,507,552.42–6,739,225.14), with a decreasing trend in the age-standardized mortality ratio (ASMR), which increased from 1 per 10,000 population.) showed a decreasing trend from 981.87 cases per 100,000 (95% UI, 895.79–1,042.22) to 600.08 cases per 100,000 (95% UI, 531.63–653.22), with an EAPC of −1.446 (95% UI, −1.592 to 1.3) ( Supplementary Table S3-1 ; Supplementary Table S4-1 ; Supplementary Table S6-1 ). 3.1.3 DALYs In 1990, the number of cases of DALYs in elderly males showed a gradual decreasing trend with age, and the number of cases of DALYs in males aged 60–64 years was 8,285,744.32 (95% UI, 7,630,948.93–8,935,725.70).

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showed a trendno p-value reported
The rate of stroke DALYs in older men showed a trend of an increase then followed by a decrease, and the highest rate of DALYs was in the age group of 90–94 years, which was 29,196.62 cases per 100,000 people (95% UI, 25,472.68 to 31,920.38).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.