Salvage treatment strategies for refractory sudden sensorineural hearing loss-a comprehensive review and meta-analysis with practical recommendations.

Front Neurol · 2025 · PMC12305195 · PMID 40734818

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.1510

boldest claim

The sentences

highly significantp < 0.0001actually significant

There was a significant heterogeneity among studies I 2 = 88.7% (95% CI: 76.3–94.6%), τ 2 = 17.32, and a highly significant Q -test ( p < 0.0001) ( 14 , 17–20 ).

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did not reach statistical significancep = 0.151not close (p > 0.1)

Although 14.8% ITS patients experienced gains of ≥20 dB compared to only 3.6% in the placebo group, this difference did not reach statistical significance ( p = 0.151).

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