Barely Significant
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Myonuclear alterations associated with exercise are independent of age in humans.

J Physiol · 2025 · PMC12306410 · PMID 36597809

1
hedged sentence
0.0550
closest p · 1.1× alpha
0.0550
boldest claim

The sentences

trending towards significanceP = 0.055so close (0.05 < p ≤ 0.1)
Consistent with the increase in lamin A, levels of Sad1/UNC‐84 (SUN) protein 2, SUN2, which is known to preferentially bind lamin A over lamin C (Liang et al., 2011 ), showed a 45% increase in trained mice that was trending towards significance (1129 ± 498 vs . 1639 ± 394, respectively, P = 0.055).

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