Distinct Roles of HHLA2 and PD-L1 in the Immune Cell and Prognosis of Hepatocellular Carcinoma.

J Hepatocell Carcinoma · 2025 · PMC12306544 · PMID 40734696

Europe PMC DOI

hedged sentence

0.0950

closest p · 1.9× alpha

0.0950

boldest claim

The sentences

did not reach statistical significanceP = 0.095so close (0.05 < p ≤ 0.1)

33 , 34 However, with findings from The Cancer Genome Atlas (TCGA) database, reduced level of PD-L1 mRNA (CD274) demonstrates a potential association with unfavorable prognosis in hepatocellular carcinoma (HCC) patients, although this correlation did not reach statistical significance (P = 0.095, Supplementary Figure 1B ).

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