Mpo, a marker of neutrophils, trended down with Aramchol meglumine treatment but did not reach statistical significance ( p =0.06, Supplemental Figure S4B, http://links.lww.com/HC9/C28 ).
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Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes.
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