Targeting the Menin-KMT2A interaction in leukemia: Lessons learned and future directions.

Int J Cancer · 2026 · PMC12307729 · PMID 39887730

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a clear trendno p-value reported

Querying the Cancer Dependency Map 86 , 87 for dependencies of 757 cancer cell lines on KMT2A and Menin revealed a clear trend of many cancer cell types to be dependent on KMT2A and/or Menin (Figure 5A ).

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