The study found that the biochemical response rate following one year of UDCA treatment was higher in patients with PBC/NAFLD compared to those with only PBC, although this did not reach statistical significance (Paris I criteria: 66.67% vs. 62.68%, P = 0.50; Paris I criteria: 60.92% vs. 57.61%, P = 0.59).
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Concurrent nonalcoholic fatty liver disease may decrease liver fibrosis severity in patients with primary biliary cholangitis.
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