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Norepinephrine inhibits cell cycle re-entry of neonatal rat ventricular cardiomyocytes characterized by the absence of de novo nestin expression.

Physiol Rep · 2025 · PMC12309976 · PMID 40737557

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Furthermore, PDBu/SB203580 treatment of neonatal rat ventricular cells for 24 h significantly attenuated Bub1 mRNA downregulation, whereas a modest reversal of Ect2 mRNA downregulation was also observed but did not reach statistical significance as compared to PDBu (Figure 6 ).

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