Hyperglycemia enhances group B <i>Streptococcus</i> pathogenicity by impairing TLR2 expression and chemotactic response in the human placenta.

B lymphocytes showed a trend toward decreased migration under the combined stimulus; however, this difference was not statistically significant ( Supplementary Figure 5B ). 3.4 Hyperglycemia and GBS infection impair TLR-2 expression After observing decreased cytokine and chemokine molecules, and migration of total IVMC and specific cells, by both, hyperglycemia and infection, we sought to understand the mechanism underlying this phenomenon.

also in 53,322 other papers