Amblyostatin-1, the first salivary cystatin with host immunomodulatory and anti-inflammatory properties from the Neotropical tick <i>Amblyomma sculptum</i>, vector of Brazilian spotted fever.

Front Immunol · 2025 · PMC12310653 · PMID 40746554

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did not reach statistical significanceno p-value reported

A slight decrease in the percentage of CD40 + DCs and the median fluorescence intensity (MFI) of this marker was noted in the presence of 3 μM Amblyostatin-1, although the difference did not reach statistical significance ( Figures 4A, B , respectively).

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Amblyostatin-1, the first salivary cystatin with host immunomodulatory and anti-inflammatory properties from the Neotropical tick &lt;i&gt;Amblyomma sculptum&lt;/i&gt;, vector of Brazilian spotted fever.

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Amblyostatin-1, the first salivary cystatin with host immunomodulatory and anti-inflammatory properties from the Neotropical tick <i>Amblyomma sculptum</i>, vector of Brazilian spotted fever.