Barely Significant
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An inflammatory fingerprint in mild cognitively impaired patients is reversed by physical and cognitive training.

Brain Behav Immun Health · 2025 · PMC12312118 · PMID 40746966

3
hedged sentences
0.0770
closest p · 1.5× alpha
0.0770
boldest claim

The sentences

a trend toward significancep = 0.0770so close (0.05 < p ≤ 0.1)
On the cognitive front, significant gains were observed: the ADAS-Cog scores improved in the training group (between-group mean difference at T7, p = 0.0278), with a trend toward significance in the group∗time interaction ( p = 0.0770) ( Fig. 4 B, left; eTable 7 , Supplement 2).

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borderline significanceno p-value reported
Additionally, the MCI cohort had lower fat mass (borderline significance) and a significantly higher heart rate compared to Healthy controls ( eTable 1 , Supplement 2) .

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However, trends toward increased levels of IFNγ and IL-12p70 —both proinflammatory cytokines—were observed in the MCI group, although these did not reach statistical significance after adjustment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.