Shared diagnostic genes and potential mechanisms between intervertebral disc degeneration and diabetes mellitus revealed by integrated transcriptomic analysis and machine learning.

Front Endocrinol (Lausanne) · 2025 · PMC12313482 · PMID 40756519

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did not reach statistical significanceno p-value reported

The results demonstrated significant upregulation of TCN1, LRRK2, and PRTN3 in the IDD group (p < 0.05), while the other core diagnostic genes exhibited an upward trend that did not reach statistical significance ( Figure 7A ).

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