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Gonadotoxicity of immunotherapy and targeted agents in patients with cancer and impact on subsequent pregnancies.

Hum Reprod · 2025 · PMC12314150 · PMID 40482082

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showed a trendno p-value reported
Food and Drug Administration, 2021 ), was associated with adverse ovarian effects when administered to sexually immature monkeys, including a decrease or absence of secondary and tertiary ovarian follicles; these effects showed a trend toward recovery after the end of treatment.

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