Developing Immunoniosomes (INs): Antibody and Fab conjugations of niosomal nanoparticles via UV-NBS and EDC/NHS chemistry for treating glioblastoma cells.

Although all formulations exhibited an increasing trend in negative charge upon PA loading, 0.5 % PA formulation consistently maintained a stable negative zeta potential across all niosome types, without inducing significant changes in vesicle size or increasing polydispersity.

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Although the effect on Fab-linker conjugates was less pronounced, a clear trend of decreasing binding activity was observed with increasing UV exposure duration.

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