Association of epigenetic aging with plasma biomarkers of amyloid, tau, neurodegeneration, and neuroinflammation in Hispanic/Latino adults.

Clin Epigenetics · 2025 · PMC12315259 · PMID 40750903

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marginally significantno p-value reported

Acceleration in all clocks except DunedinPACE was associated with higher plasma Aβ42 levels but only a marginally significant association with PC-PhenoAge remained after adjustment for MCI status, APOE genotype, cardiovascular risk factors, and comorbid medical conditions.

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did not reach statistical significanceno p-value reported

Age acceleration in GrimAge2 and DunedinPACE was also greater in males than females although these differences did not reach statistical significance.

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