Meta-analysis of maternal and neonatal outcomes of cannabis use in pregnancy current to March 2024.

Matern Health Neonatol Perinatol · 2025 · PMC12315265 · PMID 40745566

Europe PMC DOI

hedged sentences

0.1900

closest p · 3.8× alpha

0.1900

boldest claim

The sentences

did not reach statistical significanceP = 0.19not close (p > 0.1)

[ 66 ] from the analysis, however the outcome still did not reach statistical significance (RR = 1.08, 95% CI = (0.96, 1.22), P = 0.19) and ( P = 0.49, I 2 = 0%), as seen in Fig. 5 .

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borderline significanceno p-value reported

Compared to Lo 2023, which found no clear cannabis-only mortality link, our increased perinatal mortality (RR = 1.72, 95% CI = 1.09–2.71) suggests newer studies may amplify this signal, though with borderline significance.

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