30-hydroxygambogic acid increases the efficacy of cisplatin in an HPV<sup>+</sup> head and neck cancer in vivo model.

However, creatine kinase continued to exhibit a highly significant increase in group [D] vs. group [C] (*** p = 0.0005) (Fig. 5 C-b).

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Additionally, when compared with the single-treated cisplatin [C], the combined treatment [D] had an appreciable elevation of AST that did not reach statistical significance ( p = 0.1265) (Fig. 5 C-a).

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