Barely Significant
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Differential effects of GLP-1 receptor agonists on diabetic osteopathy in type 2 diabetes: a patient-stratified network meta-analysis.

BMC Musculoskelet Disord · 2025 · PMC12315457 · PMID 40751153

Europe PMCDOI
2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

highly significantP-value < 0.001actually significant
Furthermore, while GLP-1 RAs reduced bone resorption (β-CTX SMD −1.43 [−2.01, −0.86]), SGLT2 inhibitors increased it (SMD + 0.52 [−0.01, 1.05]), resulting in a highly significant difference (P-value < 0.001).

also in 132,142 other papers

did not reach statistical significanceno p-value reported
The effect on P1NP, another formation marker, was positive but did not reach statistical significance (SMD 0.14 [−0.03, 0.31]).

also in 111,027 other papers

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