OGG1 augments the transcriptional activation of <i>Foxp3</i> to promote iTreg differentiation for IBD alleviation.

The frequency of OGG1 S326C allele was 51.8% in IBD patients compared to 61.6% in healthy control subjects, indicating a trend toward a protective association, although this did not reach statistical significance, the p value was 0.155 using chi-squared test analysis ( SI Appendix , Fig.

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