Barely Significant
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Potential intermediate-term survival differences among heart transplant recipients from circulatory death vs brain death donors.

JHLT Open · 2025 · PMC12318337 · PMID 40756005

1
hedged sentence
0.2200
closest p · 4.4× alpha
0.2200
boldest claim

The sentences

did not reach statistical significancep = 0.22not close (p > 0.1)
A previous study using UNOS registry reported a lower 2-year survival for DCD (80%) as compared to DBD recipients (88%) but the difference did not reach statistical significance ( p = 0.22) given the smaller sample size of 425 DCD and 850 DBD heart transplants as compared to ours. 9 A multicenter retrospective observational study from 15 major transplant centers in the UK, Spain, United States, and Belgium with 157 DCD heart transplants reported similar survival between DCD and DBD in the first 5 years but looking at their Kaplan-Meier graphs in Figure 2 , DCD line crossed and went under DBD line after year 6. 25 To our knowledge, our study is the largest analysis of DCD heart transplant survival published to date.

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