MiR-132 inhibition improves myocardial strain in a large animal model of chronic left ventricular adverse remodelling.

The absolute value of GLS had a significant positive linear correlation with LVEF at Month 4 ( r = 0.4649; P = 0.0224) and Month 6 ( r = 0.4625; P = 0.0231) and with LVESV at Month 6 ( r = −0.5246; P = 0.0106), while the association of PAS was overall less strong, but a clear trend was recognized ( Figure 4A–D , Supplementary data online , Table S1 ).

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