Although IgA + B220 + B cells showed a trend towards reduction in naïve Bank1 -/- SILP, it did not reach significance ( Figure 3A right).
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<i>Bank1</i> deficiency reshapes the gut microbiota of lupus mice towards an anti-inflammatory composition.
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Similarly, the mLN showed a nonsignificant trend towards increased production of IL-10 by B cells in IMQ-treated P. distasonis -gavaged WT mice in comparison to IMQ-treated PBS-gavaged WT mice ( Supplementary Figure S6G ).