Impact of hippocampal α-synuclein oligomers on cognitive trajectory in patients with dementia with Lewy bodies.

Alzheimers Dement · 2025 · PMC12319237 · PMID 40755115

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

did not reach statistical significancep = 0.057so close (0.05 < p ≤ 0.1)

A trend toward higher αSYN oligomer burden in the CA2 region was observed in the rapid cognitive decline group compared to the slow cognitive decline group, although this difference did not reach statistical significance (median %area 1.97 vs. 1.11; p = 0.057).

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