Daily average prednisolone dose per month in the 6 months before and after TPO-RA initiation The early TPO-RA initiation group showed a trend toward a gradual increase in prednisolone dose before TPO-RA administration, followed by a decrease ( Figure 2 ; supplemental Figure 4 ).
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Japanese database analysis: effectiveness of early initiation of TPO-RA treatment in tapering corticosteroid dose in ITP.
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When analyzed by age, there was an overall trend toward a higher incidence of AEs in patients aged ≥60 years ( Table 5 ).