Barely Significant
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Evolution of the burden of disease for high BMI-associated colorectal cancer, 1990-2021: Global trends, regional heterogeneity, and population risk stratification.

Prev Med Rep · 2025 · PMC12320544 · PMID 40761337

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a decreasing trendno p-value reported
an increasing trendno p-value reported
A positive EAPC indicates an increasing trend, while a negative EAPC indicates a decreasing trend.

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showed a trendno p-value reported
However, the absolute number of cases and standardized rates in low and middle SDI regions still showed a trend of “double increase”, especially in Southeast Asia and East Asia, where the number of deaths increased by more than 5-fold, a trend that is consistent with the results of previous studies ( Ncd-Risc, 2017 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.