The value of multiparametric MRI-based combined intratumoral and peritumoral radiomics in differentiating luminal and non-luminal molecular subtypes of breast cancer: a multicenter study.

Notably, while the multiparametric intratumoral-peritumoral integrated model showed numerically higher AUC values than the optimal single-parameter model (T2WI_Peri3 RF), this difference did not reach statistical significance (P>0.05), suggesting complementary rather than mutually exclusive diagnostic value between single-parametric and multi-parametric approaches.

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