Immune-Checkpoint Inhibitors in Lung Neuroendocrine Tumors - A Systematic Review and Meta-Analysis.

Onco Targets Ther · 2025 · PMC12325105 · PMID 40772040

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

borderline significantp-value = 0.056so close (0.05 < p ≤ 0.1)

However, we observed a borderline significant difference when comparing ICI monotherapy with dual/combination strategies (p-value = 0.056) in favor of the latest.

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showed a trendno p-value reported

Subgroup analysis by intervention types showed a trend for lower ORR of lung NETs treated with ICI monotherapy (ORR: 2.7%; 0.0–63.7) compared with combinations (p-value: 0.056).

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