a positive trendp = 0.07
The findings indicated that vaginal administration was significantly associated with HPV lesion resolution (RR = 2.21, 95% CI: 1.57–3.11, p < 0.00001; I 2 = 0%), whereas oral administration showed a positive trend that did not reach statistical significance (RR = 1.51, 95% CI: 0.96–2.38, p = 0.07; I 2 = 0%).