Whilst the results supported the enrichment trends observed in our RNA‐seq analysis for selected transcripts, including MT‐ND4 ( p = 0.21), HIST1H1A ( p = 0.23), IGSF8 ( p = 0.09), XIST ( p = 0.11) and miR‐7‐5p ( p = 0.55) the differences between ADiNEVs and iNEVs did not reach statistical significance. 4 Discussion A primary goal of AD research is to prevent or slow progressive neurodegeneration before the emergence of symptomatic cognitive decline.
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Profiling RNA Cargo in Extracellular Vesicles From hiPSC-Derived Neurons of Alzheimer's Disease Patients.
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