Acetylsalicylic acid and vorapaxar are less active, while 4-methylcatechol is more active, in type 1 diabetic patients compared to healthy controls.

n between healthy and diabetic persons were insignificant in whole donor analysis ( p = 0.09), but achieved significance after exclusion of hypertensive subjects from both groups ( p = 0.047, lower aggregation in T1D group), (3) The effect of ticagrelor on ADP-induced platelet aggregation which was nearly significant when all donors were analysed ( p = 0.051) and insignificant ( p = 0.09) when all hypertensive cases were excluded, became significant ( p = 0.025) when solely “healthy” hypertensive volunteers were excluded.

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