Integrated molecular and detailed anatomical profiling identifies a prognostically adverse subtype of posterior fossa meningiomas: high-risk copy number alterations are associated with midline predilection and predict poor prognosis.

Acta Neuropathol Commun · 2025 · PMC12329998 · PMID 40775657

Europe PMC DOI

hedged sentence

0.3300

closest p · 6.6× alpha

0.3300

boldest claim

The sentences

did not reach statistical significanceP = 0.33not close (p > 0.1)

A similar trend toward shorter PFS was observed for Group C tumors among patients who underwent STR, although the difference did not reach statistical significance ( P = 0.33).

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