Age-Related Increase in Locus Ceruleus Activity and Connectivity with the Prefrontal Cortex during Ambiguity Processing.

J Neurosci · 2025 · PMC12330320 · PMID 40588355

Europe PMC DOI

hedged sentence

0.0860

closest p · 1.7× alpha

0.0860

boldest claim

The sentences

showed a trendp = 0.086so close (0.05 < p ≤ 0.1)

LC–dlPFC connectivity and task-independent stress scores Across all participants, stronger left LC–right dlPFC connectivity showed a trend-level negative association with lower self-reported stress scores ( r = −0.15, p = 0.086, 95% CI: [−0.31, 0.002]).

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