Barely Significant
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Semaglutide in Heart Failure With Preserved Ejection Fraction: Emerging Evidence and Clinical Implications.

Cureus · 2025 · PMC12333672 · PMID 40786355

1
hedged sentence
0.1200
closest p · 2.4× alpha
0.1200
boldest claim

The sentences

showed a trendP = 0.12not close (p > 0.1)
2.7% of placebo (HR 0.61, 95% CI 0.38-0.99, P = 0.04), while nonfatal MI showed a trend toward reduction (2.9% vs. 3.9%, HR 0.74, 95% CI 0.51-1.08, P = 0.12).

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