Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics.

Nat Commun · 2025 · PMC12334592 · PMID 40781077

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Because the maximum of nuclear RelA fold change did not show a strong trend between pulse-trains and dose-conserving single-pulses, we focused on scoring rates of nuclear RelA export (Fig. 3d and Supplementary Fig. 4a ).

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