Cancer stem cells and Lon-noncRNA promotes invasion, metastasis and tumor growth in breast cancer through regulation of signaling pathway.

The highly significant overexpression of both genes ( p < 0.001) combined with substantial fold-changes (SNAIL: 2.55, FOXC2: 2.70) establishes these molecules as reliable indicators of metastatic disease progression and represents a major advancement in understanding breast cancer stem cell biology.

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Patients with high ZEB (54%) and UCA1 (54.5%) expression had slightly improved survival probabilities compared to those with low expression (22.8% and 35%, respectively), but these differences did not reach statistical significance.

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