Non-coding genetic elements of lung cancer identified using whole genome sequencing in 13,722 Chinese.

Nat Commun · 2025 · PMC12335547 · PMID 40783572

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

marginally significantP = 0.061so close (0.05 < p ≤ 0.1)

Among the top-ranked genes identified in the discovery stage, marginally significant associations were observed for MYO5B ( P = 0.061, promoter/enhancer) and AUTS2 ( P = 0.089, synonymous) in the replication stage.

also in 26,082 other papers

highly significantno p-value reported

Assuming the regulatory role of the identified segments, promising results were found given the highly significant enrichment of enhancer signals in lung and immune-related cell lines.

also in 132,142 other papers

nominally significantno p-value reported

i.e., nominally significant associations were observed in a different category in the replication stage.

also in 7,732 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.