Barely Significant
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Molecular profile and clinical impact of MDM2 amplification in patients with advanced biliary tract cancer.

ESMO Open · 2025 · PMC12335989 · PMID 40743751

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showed a trendno p-value reported
For OS, MDM2 -amp/ TP53 -WT status showed a trend toward favorable survival; however, the result was not statistically significant (HR 0.70, 95% CI 0.48-1.02, P = 0.065) ( Table 2 ).

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