Barely Significant
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Global trends in the burden of alcohol use disorders in the working-age population from 1990 to 2021 and projections for the next 20 years.

Front Public Health · 2025 · PMC12336152 · PMID 40791621

Europe PMCDOI
2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

showed a trendp < 0.001actually significant
In terms of regions, from 1990 to 2021, the disease burden in areas with a medium--to-high socio-demographic index (SDI) was greater, and this trend was particularly pronounced in Eastern Europe.Disease burden and SDI level showed a trend of stage correlation, ASDR ( R = 0.28, p < 0.001).

also in 53,322 other papers

a decreasing trendno p-value reported
Specifically, both indicators shifted from a decline to an increase in 1998, while 1994 and 2004 marked the transition from an increasing to a decreasing trend.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.