Barely Significant
← all excerpts

Blood Microbiome Reveals the Impact of <i>Lactobacillus</i> on the Efficacy of Immunotherapy in Gastrointestinal Cancer.

MedComm (2020) · 2025 · PMC12336454 · PMID 40791867

Europe PMCDOI
2
hedged sentences
0.0740
closest p · 1.5× alpha
0.0740
boldest claim

The sentences

showed a trendp = 0.074so close (0.05 < p ≤ 0.1)
As expected, we found that patients with lower baseline observed species and Chao1 indices had significantly prolonged PFS ( p = 0.0015 for observed species and p = 0.013 for Chao1, Figure 1C ), and patients with a lower Shannon index also showed a trend towards increased PFS ( p = 0.074, Figure 1C ) in those who received immunotherapy combined with chemotherapy.

also in 53,322 other papers

a decreasing trendno p-value reported
Proteobacteria were the dominant phylum across all groups, with minimal changes before and after chemotherapy but a decreasing trend after immunotherapy combined with chemotherapy.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.