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Oncolytic herpes simplex virus reprograms cancer-associated fibroblasts to enhance antitumor immunity in pancreatic cancer.

Mol Ther Oncol · 2025 · PMC12337124 · PMID 40791814

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Although CD40 expression was upregulated in PSCs, this increase did not reach statistical significance; however, the expression level of CD40 in PSCs was notably higher than in KPC cells ( Figures 5 H and 5I).

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