Efficacy and Safety of Pulsed-Field Versus High-Power Short-Duration Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis With Reconstructed Time-to-Event Data.

However, upon subgrouping the studies regarding the follow‐up periods, PFA was significantly associated with a 25% reduction in ATA recurrence compared to HPSD ablation (45–90 W) at 1 year (RR: 0.75 with 95% CI [0.61, 0.92], p < 0.01); PFA showed a trend toward an association with a lower incidence of ATA recurrence but not significant compared to HPSD ablation (45–90 W) at 6 months (RR: 0.65 with 95% CI [0.43, 1.00], p = 0.05) (Figure 1B ).

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