Efficacy of additional ExTRa Mapping-guided substrate ablation beyond pulmonary vein isolation in persistent atrial fibrillation: The ROTATE trial.

J Cardiovasc Electrophysiol · 2025 · PMC12337631 · PMID 40548679

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did not reach statistical significanceno p-value reported

Conclusion While the reduction in atrial tachyarrhythmia recurrence of persistent AF patients did not reach statistical significance, the addition of ExTRa MappingTM‐guided substrate ablation beyond PVI demonstrated promising potential, especially in patients with larger rotational activation areas.

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