Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses.

Br J Psychiatry · 2025 · PMC12337998 · PMID 39806801

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantP < 1.0 × 10 −16actually significant

Although it displays limited power, the PRS predictor is highly significant ( P < 1.0 × 10 −16 ), and an analysis of variance (ANOVA) between the full PRS model against the null model using covariates only is significant ( P = 1.9 × 10 −12 ), confirming the additional classification accuracy conferred by the PRS predictor.

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nominally significantP < 0.001actually significant

Nominally significant pathways ( P < 0.001) are listed in Supplementary Tables 9(a) – (d) .

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