Predicting Bone Metastasis in Prostate Cancer Patients Using Total Serum Prostate-Specific Antigen and Serum Alkaline Phosphatase: Model Development, Validation, and Deployment as a Digital Risk Estimator.

Cureus · 2025 · PMC12338857 · PMID 40792342

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

approached significancep = 0.061so close (0.05 < p ≤ 0.1)

ALPcat (adjusted odds ratios [aOR]: 3.29), PSAcat (aOR: 2.84), and ISUP (aOR: 1.92) were statistically significant predictors (p < 0.001), while DREcat approached significance (p = 0.061).

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highly significantno p-value reported

The pseudo R2 of 0.518 and highly significant LLR p-value (<0.0001) indicated good model fit.

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