Improvement in body composition of Japanese participants with Prader-Willi syndrome following somatropin treatment: an open-label, multi cohort Phase 3 study.

In this study, Cohort 2 showed a trend toward lower subcutaneous and visceral adipose tissue following treatment with somatropin, consistent with a previous study comparing somatropin with placebo in adults with PWS and further demonstrating the beneficial impact of somatropin on body composition parameters [ 9 ].

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