Differences and similarities between the genetic architecture of lifetime substance use across different substances.

In AMR, rs11699278 – an intronic variant of CYP24A1 , a gene involved in the regulation of vitamin D and calcium homeostasis (Jones, Prosser, & Kaufmann, 2012 ) – was associated with Inhalants LU; it did not have high LD with any significant (or nearly significant) SNPs ( Supplementary Figure S4 ), so this finding might be a false-positive.

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