Comparative performance of a commercial and in-house Mp1p antigen-detecting enzyme immunoassay for the rapid diagnosis of talaromycosis.

PLoS Negl Trop Dis · 2025 · PMC12342302 · PMID 40749024

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closest p · 1.2× alpha

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did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

The Wantai Mp1p EIA had slightly lower power in discriminating between disease and no disease in urine compared to the in-house Mp1p EIA, with AUC of 92.5% (95% CI 89.6 – 95.4%) vs 95.4% (95% CI 93.3 –97.5%), but the difference did not reach statistical significance P = 0.06.

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